Description

(2R,4S)-3-Benzoyl-4-Ethoxylcarbonylmethyl-4-Methyl-5-Oxazolidinone is a high-purity, chiral oxazolidinone derivative that serves as a critical building block in asymmetric synthesis. Its value lies in its role as a versatile chiral auxiliary and intermediate for the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• As a chiral auxiliary in asymmetric aldol, alkylation, and Diels-Alder reactions for constructing complex molecular architectures.
• A key synthetic intermediate in the production of active pharmaceutical ingredients (APIs), particularly β-lactam antibiotics and other nitrogen-containing heterocycles.
• Utilized in methodology development for stereoselective synthesis within academic and industrial research laboratories.
• Potential use in the synthesis of agrochemicals and specialty chemicals where chirality impacts biological activity.
• As a reference standard for analytical method development and quality control in chiral separation techniques like HPLC.

Basic Information

Product Name	(2R,4S)-3-Benzoyl-4-Ethoxylcarbonylmethyl-4-Methyl-5-Oxazolidinone
CAS No.	113806-36-3
Molecular Formula	C15H17NO5
Molecular Weight	291.30 g/mol
Synonyms	(4S)-3-Benzoyl-4-[(ethoxycarbonyl)methyl]-4-methyl-1,3-oxazolidin-5-one; (2R,4S)-3-Benzoyl-4-(ethoxycarbonylmethyl)-4-methyl-5-oxazolidinone; (4S)-3-Benzoyl-4-(carbethoxymethyl)-4-methyl-2-oxazolidinone; Evans Auxiliary Derivative; Chiral Oxazolidinone Auxiliary; Benzoyl Evans Auxiliary; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (2R,4S)-3-Benzoyl-4-Ethoxylcarbonylmethyl-4-Methyl-5-Oxazolidinone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and chiral purity are available upon request to support your quality and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; therefore, it should be handled in a dry environment and the container kept tightly sealed after each use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.