Description

4-Fluorotranylcypromine is a fluorinated derivative of the monoamine oxidase inhibitor (MAOI) tranylcypromine, identified by CAS number 113516-71-5. This compound is a critical pharmaceutical intermediate and a valuable research chemical for investigating the structure-activity relationships of MAO inhibitors. It is primarily utilized by pharmaceutical R&D organizations, academic research institutions, and contract synthesis facilities focused on neuropharmacology and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antidepressant and neuropsychiatric drug candidates.
• Biochemical Research: Tool compound for studying monoamine oxidase (MAO) enzyme inhibition mechanisms and selectivity.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to optimize potency and pharmacokinetic properties of MAO inhibitors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Preclinical Development: Employed in early-stage in vitro and in vivo pharmacological profiling of potential central nervous system (CNS) active compounds.

Basic Information

Product Name	4-Fluorotranylcypromine
CAS No.	113516-71-5
Molecular Formula	C9H10FN
Molecular Weight	151.18 g/mol
Synonyms	(1R,2S)-2-Phenylcyclopropan-1-amine, 4-Fluoro-; 4-Fluoro-(1R,2S)-2-phenylcyclopropan-1-amine; 4-Fluoro-trans-2-phenylcyclopropylamine; 4-Fluoro-TCP; 4-F-TCP; 4-Fluorotranylcypromine HCl (for salt forms); PCPA, 4-Fluoro-
EINECS	Contact for details

Quality Control

Our 4-Fluorotranylcypromine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.