Description

D(+)-Vesamicol Hydrochloride is a high-purity, enantiomerically pure organic compound widely recognized for its specific biological activity. This compound is a critical research chemical and pharmaceutical intermediate, valued for its role in studying vesicular acetylcholine transport systems. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in neuroscience and neuropharmacology.

Application

• Neuroscience Research: A key tool compound for investigating the vesicular acetylcholine transporter (VAChT) and cholinergic neurotransmission.
• Pharmacological Studies: Used in vitro and in vivo to study the mechanisms of cholinergic system modulation and related disorders.
• Pharmaceutical Intermediate: Serves as a chiral building block in the synthesis of more complex molecules targeting neurological pathways.
• Reference Standard: Employed as a certified reference material (CRM) in analytical laboratories for method development and validation.
• Biochemical Assay Development: Used in high-throughput screening (HTS) to identify and characterize new drug candidates affecting acetylcholine storage and release.

Basic Information

Product Name	D(+)-Vesamicol Hydrochloride
CAS No.	112709-60-1
Molecular Formula	C19H28ClNO
Molecular Weight	321.89 g/mol
Synonyms	(+)-Vesamicol HCl; (2R,3S)-2-(4-Phenylpiperidino)cyclohexanol Hydrochloride; D-Vesamicol Hydrochloride; (+)-trans-2-(4-Phenylpiperidino)cyclohexanol Hydrochloride; AH-5183; P-99; Vesamicol (D-isomer) Hydrochloride
EINECS	Contact for details

Quality Control

Our D(+)-Vesamicol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) providing results for identity, purity, and impurities is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.