Description

4-Bromo-2-Fluorobenzoic Acid is a high-purity halogenated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile molecular scaffold with orthogonal reactive sites for constructing complex pharmaceutical intermediates and agrochemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality raw materials for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and brominated aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine and bromine substituents modulate biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.
• Ligand & Catalyst Development: The carboxylic acid functionality allows for derivatization into chelating ligands for metal catalysts.

Basic Information

Product Name	4-Bromo-2-Fluorobenzoic Acid
CAS No.	112704-79-7
Molecular Formula	C7H4BrFO2
Molecular Weight	219.01 g/mol
Synonyms	2-Fluoro-4-bromobenzoic Acid; 4-Bromo-2-fluorobenzoic Acid; Benzoic acid, 4-bromo-2-fluoro-; 4-Bromo-2-fluorobenzenecarboxylic Acid; 2-Fluoro-4-bromobenzenecarboxylic Acid; 4-Bromo-2-fluoro-benzoic acid; 4-Bromo-2-fluorobenzoic acid, 98+%
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluorobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	162°C - 166°C
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.