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(2S,4S)-(-)-2-(Diphenylphosphinomethyl)-4-(Dicyclohexylphosphino)-n-Methyl-1-Pyrrolidinecarboxamide, Min. 97% (S,S-Mccpm) CAS NO 112521-97-8


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CAS No.:112521-97-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2S,4S)-(-)-2-(Diphenylphosphinomethyl)-4-(Dicyclohexylphosphino)-n-Methyl-1-Pyrrolidinecarboxamide, Min. 97% (S,S-Mccpm) is a high-purity, chiral phosphine ligand essential for advanced asymmetric catalysis. This compound matters because it enables highly selective and efficient synthesis of complex chiral molecules, which are critical for developing active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require precise stereochemical control in their synthetic processes.

Application

  • Asymmetric Hydrogenation: A key ligand for the enantioselective reduction of prochiral olefins, ketones, and imines in API synthesis.
  • Pharmaceutical Intermediate Synthesis: Enables the production of chiral building blocks for drugs targeting central nervous system, cardiovascular, and metabolic diseases.
  • Agrochemical Manufacturing: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
  • Cross-Coupling Catalysis: Facilitates asymmetric versions of Suzuki, Heck, and other cross-coupling reactions for C-C bond formation.
  • Academic & Process Chemistry Research: A valuable tool for developing new catalytic methodologies and optimizing reaction pathways in R&D laboratories.
  • Fine Chemical Production: Applied in the manufacture of chiral flavors, fragrances, and advanced materials.

Basic Information

Product Name (2S,4S)-(-)-2-(Diphenylphosphinomethyl)-4-(Dicyclohexylphosphino)-n-Methyl-1-Pyrrolidinecarboxamide, Min. 97% (S,S-Mccpm)
CAS No. 112521-97-8
Molecular Formula C31H43N2OP2
Molecular Weight 512.63 g/mol
Synonyms (S,S)-MCCPM; (S,S)-Mccpm; (2S,4S)-MCCPM; (S,S)-2-(Diphenylphosphinomethyl)-4-(dicyclohexylphosphino)-N-methylpyrrolidinecarboxamide; (S,S)-(-)-2-(Diphenylphosphinomethyl)-4-(dicyclohexylphosphino)-N-methyl-1-pyrrolidinecarboxamide; (S,S)-Methyl Carboxamide Cyclohexyl Phenyl Phosphine; S,S-MCCPM Ligand; Chiral Phosphine Ligand MCCPM
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Quality Control

Our (S,S)-MCCPM is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for chiral purity and assay, NMR for structural confirmation, and elemental analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, and well-ventilated place. This product is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided to maintain stability and efficacy.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) Min. 97.0%
Chiral Purity (HPLC) Min. 99.0% ee
Water Content (KF) Max. 0.5%
Residue on Ignition Max. 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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