Description

20-Carboxy-n-Acetylleukotriene E4 is a specialized leukotriene metabolite and a key analytical standard for research in eicosanoid biology. This compound is essential for scientists and pharmaceutical developers investigating inflammatory pathways, asthma, and allergic responses. It is primarily used in biochemical research, diagnostic assay development, and as a reference material in high-purity analytical applications.

Application

• Biochemical Research Standard: Used as a high-purity reference standard in the study of leukotriene metabolism and eicosanoid signaling pathways.
• Diagnostic Development: Serves as a critical calibrant and control in the development of immunoassays (ELISA, RIA) for quantifying leukotriene metabolites in biological samples.
• Pharmaceutical R&D: Employed in drug discovery programs targeting inflammatory diseases such as asthma, allergic rhinitis, and other conditions mediated by cysteinyl leukotrienes.
• Metabolite Analysis: A vital analytical standard for LC-MS/MS and HPLC methods used to profile leukotriene E4 metabolites in clinical and pre-clinical studies.
• Academic Research: Supports fundamental research in pharmacology, immunology, and cell biology to elucidate the role of leukotrienes in disease mechanisms.

Basic Information

Product Name	20-Carboxy-n-Acetylleukotriene E4
CAS No.	112066-58-7
Molecular Formula	C27H41NO9S
Molecular Weight	555.68 g/mol
Synonyms	20-COOH-N-Acetyl-LTE4; 20-Carboxy-N-acetylleukotriene E4; N-Acetyl-20-carboxyleukotriene E4; 20-Carboxy-N-acetyl-LTE4; LTE4 20-Carboxylic Acid N-Acetyl Derivative; 20-Carboxy-N-acetyl-LTE4; N-Acetyl-20-carboxy-LTE4; 20-Carboxy-N-acetyl-LTE4 (112066-58-7)
EINECS	Contact for details

Quality Control

Our 20-Carboxy-n-Acetylleukotriene E4 is produced under strict quality management protocols to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive analytical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant guidelines for reference standard materials to support your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated at the recommended temperature.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in methanol, ethanol; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.