Description

trans-2-(4-Fluorobenzoyl)-1-Cyclohexane-Carboxylic Acid, 99 CAS NO 111857-42-2 is a high-purity, fluorinated carboxylic acid derivative that serves as a critical chiral building block in advanced organic synthesis. Its defined stereochemistry and functional groups make it an invaluable intermediate for constructing complex molecules with high precision. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorobenzoyl moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex fluorinated organic compounds for specialty chemical applications.
• Academic and Industrial Research: A valuable reference standard and starting material for methodological studies in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Item	Details
Product Name	trans-2-(4-Fluorobenzoyl)-1-Cyclohexane-Carboxylic Acid, 99
CAS No.	111857-42-2
Molecular Formula	C14H15FO3
Molecular Weight	250.27 g/mol
Synonyms	trans-2-(4-Fluorobenzoyl)cyclohexanecarboxylic Acid; (1R,2R)-2-(4-Fluorobenzoyl)cyclohexanecarboxylic Acid; (1S,2S)-2-(4-Fluorobenzoyl)cyclohexanecarboxylic Acid; 2-(4-Fluorobenzoyl)cyclohexane-1-carboxylic Acid; 4-Fluoro-α-oxo-benzenepropanoic Acid, trans-2-Carboxycyclohexyl Ester; 111857-42-2; FCBA-Cyclohexane Acid
EINECS	Contact for details

Quality Control

Our trans-2-(4-Fluorobenzoyl)-1-Cyclohexane-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the specified 99% minimum purity and consistent stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 99.0%
Chiral Purity (HPLC)	≥ 99.0% de (trans-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.