Description

1-(2-Amino-3-Hydroxy-4-(Hydroxymethyl)Cyclopentyl)-2(1H)-Pyrimidinone is a high-purity nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate in the creation of novel antiviral and anticancer therapeutics. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of modified nucleosides and nucleotide-based active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the development of potential therapeutic agents targeting viral polymerases and reverse transcriptases.
• Oncology Research: Serves as a precursor in the creation of nucleotide-based chemotherapeutic candidates.
• Biochemical Research: Employed in studies of enzyme mechanisms, particularly those involving nucleotide metabolism and DNA/RNA synthesis.
• Process Chemistry Development: Utilized for scaling up synthetic routes to complex nucleoside derivatives under GMP or non-GMP conditions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in API manufacturing.

Basic Information

Product Name	1-(2-Amino-3-Hydroxy-4-(Hydroxymethyl)Cyclopentyl)-2(1H)-Pyrimidinone
CAS No.	111795-60-9
Molecular Formula	C10H15N3O3
Molecular Weight	225.25 g/mol
Synonyms	Carbocyclic Cytidine; Cyclopentyl Cytidine Analog; c-Cytidine; 2(1H)-Pyrimidinone, 1-(2-amino-3-hydroxy-4-(hydroxymethyl)cyclopentyl)-; Carbocyclic nucleoside intermediate; Anti-viral nucleoside precursor; 1-[(1S,2S,3R,4R)-2-Amino-3-hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 1-(2-Amino-3-Hydroxy-4-(Hydroxymethyl)Cyclopentyl)-2(1H)-Pyrimidinone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All batches are supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by HPLC, NMR, and mass spectrometry. We adhere to industry-standard analytical protocols and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.