Description

1-((1R,3S,6S)-6-Methyl-7-Oxabicyclo[4.1.0]Heptan-3-Yl) Ethanone is a high-purity, stereochemically defined chiral building block featuring a complex oxabicyclo[4.1.0]heptane scaffold. This compound is valued for its rigid, three-dimensional structure which is critical for imparting specific biological activity and stereochemical control in advanced synthetic pathways. It serves as a key intermediate for research and development in the pharmaceutical and agrochemical industries, particularly in the synthesis of novel active ingredients where precise spatial orientation of functional groups is paramount.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new drug candidates, especially in areas requiring complex, constrained molecular architectures.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the specific stereochemistry can influence biological efficacy and environmental selectivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands used in asymmetric synthesis to produce enantiomerically pure compounds.
• Fragrance and Flavor Chemistry: The oxabicyclic structure can be utilized in the synthesis of unique odorants and flavoring agents with specific sensory profiles.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with specialized thermal or mechanical properties derived from its rigid core.
• Academic and R&D Laboratories: Employed as a reference standard and a sophisticated building block in methodological development and total synthesis projects.

Basic Information

Product Name	1-((1R,3S,6S)-6-Methyl-7-Oxabicyclo[4.1.0]Heptan-3-Yl) Ethanone
CAS No.	111613-38-8
Molecular Formula	C10H16O2
Molecular Weight	168.23 g/mol
Synonyms	(1R,3S,6S)-6-Methyl-7-oxabicyclo[4.1.0]heptan-3-yl methyl ketone; 3-Acetyl-6-methyl-7-oxabicyclo[4.1.0]heptane; 1-[(1R,3S,6S)-6-Methyl-7-oxabicyclo[4.1.0]hept-3-yl]ethanone; (1R,3S,6S)-3-Acetyl-6-methyl-7-oxabicyclo[4.1.0]heptane; Chiral oxabicycloheptanone derivative; 7-Oxabicyclo[4.1.0]heptane-3-acetic acid, α-methyl-, methyl ester (related); Bicyclic ketone intermediate CAS 111613-38-8
EINECS	Contact for details

Quality Control

Every batch of 1-((1R,3S,6S)-6-Methyl-7-Oxabicyclo[4.1.0]Heptan-3-Yl) Ethanone is manufactured under strict quality management systems. We employ advanced analytical techniques including Chiral HPLC, GC, and NMR to ensure identity, purity, and enantiomeric excess meet exacting customer specifications. Certificates of Analysis (COA) detailing all critical parameters are provided with each shipment. Our production adheres to cGMP standards where applicable, ensuring reliable supply for critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid / solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.