Description

Cholesterol-3-Octanoate (Octanoate-1-13C, 99%) is a high-purity, isotopically labeled derivative of cholesterol, where the octanoate moiety is enriched with Carbon-13 at the 1-position. This compound is specifically engineered for use as a critical internal standard and tracer in advanced analytical and metabolic research, ensuring unparalleled accuracy in quantification. It is an essential reagent for scientists and quality control professionals in the pharmaceutical, clinical diagnostics, and life science research sectors who require precise measurement of cholesterol esters and related metabolic pathways.

Application

• Mass Spectrometry Internal Standard: Used for the accurate quantification of cholesterol and its esters in biological samples via GC-MS or LC-MS/MS, correcting for instrument variability and matrix effects.
• Metabolic Pathway Tracing: Serves as a stable isotope-labeled tracer in research studies investigating lipid metabolism, absorption, and transport in vivo and in vitro.
• Pharmaceutical R&D: Employed in the development and validation of analytical methods for lipid-based drug formulations and metabolic disease therapeutics.
• Clinical Diagnostics: Critical for calibrating assays that measure cholesterol ester levels in patient serum, supporting cardiovascular disease risk assessment.
• Nutraceutical & Food Science: Used in studies analyzing the stability, bioavailability, and metabolic fate of fortified cholesterol esters in functional foods and supplements.
• Biomarker Research: Facilitates the discovery and validation of cholesterol ester signatures as potential biomarkers for various disease states.

Basic Information

Product Name	Cholesterol-3-Octanoate (Octanoate-1-13C, 99%)
CAS No.	110888-06-7
Molecular Formula	C35H5813CO2
Molecular Weight	~ 555.9 g/mol (exact mass varies with 13C enrichment)
Synonyms	Cholesteryl Octanoate-1-13C; 5-Cholesten-3β-yl Octanoate-1-13C; 3β-Cholest-5-en-3-yl Octanoate-1-13C; Cholesteryl Caprylate-1-13C; Octanoic-1-13C Acid Cholesteryl Ester; [1-13C]Octanoic Acid Cholesterol Ester; Cholesterol Ester (8:0-1-13C); Stable Isotope Labeled Cholesterol Octanoate
EINECS	Contact for details

Quality Control

Every batch of our Cholesterol-3-Octanoate (Octanoate-1-13C, 99%) is produced and analyzed under strict quality protocols to ensure identity, purity, and isotopic enrichment meet the exacting standards required for research and analytical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), isotopic purity (NMR/MS), and chemical purity. Our quality system is designed to support compliance with cGMP and ISO guidelines for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. For long-term storage under inert atmosphere, sealed ampules are recommended. Keep the container in a dry, well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 99.0%
Isotopic Enrichment (13C at 1-position)	≥ 99 atom % 13C
Chemical Purity (by GC)	≥ 99.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.