Description

2-Amino-1,9-Dihydro-9-(2-Fluoro-3-Hydroxy-4-(Hydroxymethyl)Cyclopentyl)-6H-Purin-6-One is a high-purity, advanced pharmaceutical intermediate with a complex nucleoside-like structure. This compound is critical for the research and development of novel antiviral and anticancer therapeutics, offering a sophisticated building block for targeted drug synthesis. It is essential for pharmaceutical R&D laboratories, biotechnology firms, and fine chemical manufacturers focused on developing next-generation nucleoside analogs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel antiviral and anticancer nucleoside analog drugs.
• Antiviral Drug Research: Used in the development of therapeutic agents targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a precursor for investigational compounds designed to inhibit cancer cell proliferation.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate nucleotide metabolism pathways.
• Process Chemistry Development: Utilized for scaling up and optimizing synthetic routes for complex active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical manufacturing.

Basic Information

Product Name	2-Amino-1,9-Dihydro-9-(2-Fluoro-3-Hydroxy-4-(Hydroxymethyl)Cyclopentyl)-6H-Purin-6-One
CAS No.	110289-24-2
Molecular Formula	C11H14FN5O3
Molecular Weight	283.26 g/mol
Synonyms	9-[(1S,2R,3S,4R)-2-Fluoro-3-hydroxy-4-(hydroxymethyl)cyclopentyl]guanine; 2-Amino-9-[(1S,2R,3S,4R)-2-fluoro-3-hydroxy-4-(hydroxymethyl)cyclopentyl]-1,9-dihydro-6H-purin-6-one; (1S,2R,3S,4R)-9-(2-Fluoro-3-hydroxy-4-(hydroxymethyl)cyclopentyl)guanine; Cyclopentylguanine derivative; Fluorinated carbocyclic guanosine analog; Acyclic nucleoside phosphonate precursor; Contact for details on additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-Amino-1,9-Dihydro-9-(2-Fluoro-3-Hydroxy-4-(Hydroxymethyl)Cyclopentyl)-6H-Purin-6-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.