Description

tert-Butyl (R)-2-Hydroxybutyrate is a high-purity chiral building block and ester derivative of (R)-2-hydroxybutyric acid. This compound is valued for its role as a key synthetic intermediate in the production of optically active pharmaceuticals and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the asymmetric synthesis of various drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of chiral pesticides and herbicides where specific stereochemistry is required for biological activity.
• Fine Chemical Production: Serves as a building block for creating complex, high-value specialty chemicals, including flavors, fragrances, and advanced materials.
• Biochemical Research: Employed in metabolic studies and as a precursor in the synthesis of labeled compounds for tracer analysis.
• Asymmetric Catalysis: Acts as a substrate or ligand precursor in the development and testing of novel chiral catalysts.
• Polymer Modification: Can be used to introduce chiral centers or functional groups into polymer chains for specialized material properties.

Basic Information

Product Name	tert-Butyl (R)-2-Hydroxybutyrate
CAS No.	110171-06-7
Molecular Formula	C8H16O3
Molecular Weight	160.21 g/mol
Synonyms	(R)-2-Hydroxybutyric Acid tert-Butyl Ester; (R)-(-)-2-Hydroxybutyric Acid tert-Butyl Ester; tert-Butyl (R)-(-)-2-hydroxybutanoate; (R)-2-Hydroxybutanoic Acid tert-Butyl Ester; (R)-HBA-OtBu; (2R)-2-Hydroxybutanoic Acid 1,1-Dimethylethyl Ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (R)-2-Hydroxybutyrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.