Description

2',3'-Dideoxy-2'-Fluoroarabinofuranosyladenine is a fluorinated nucleoside analog of significant interest in pharmaceutical research and development. This compound is valued for its role as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in the development of nucleoside-based drugs targeting viral replication and cellular proliferation.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced antiviral and anticancer nucleoside analogs.
• Antiviral Research: Investigated for its potential activity against a range of DNA and RNA viruses in preclinical and clinical research settings.
• Oncology Research: Used in studies exploring nucleoside analogs that inhibit tumor cell growth by interfering with DNA synthesis.
• Biochemical Tool: Employed as a reference standard or probe in enzymatic studies to understand polymerase inhibition mechanisms.
• Process Chemistry: Utilized in scale-up and optimization processes for the commercial manufacturing of related pharmaceutical actives.

Basic Information

Product Name	2',3'-Dideoxy-2'-Fluoroarabinofuranosyladenine
CAS No.	110143-09-4
Molecular Formula	C15H17FN6O3
Molecular Weight	348.34 g/mol
Synonyms	2'-F-ara-ddA; 2'-Fluoro-2',3'-dideoxyarabinofuranosyladenine; 9-[(2R,3S,5R)-3-Fluoro-5-(hydroxymethyl)oxolan-2-yl]purin-6-amine; 2'-F-ddA; 2'-Fluoro-2',3'-dideoxyadenosine; 2'-F-2',3'-ddA; 2'-Fluoroarabinofuranosyl-2',3'-dideoxyadenine
EINECS	Contact for details

Quality Control

Our 2',3'-Dideoxy-2'-Fluoroarabinofuranosyladenine is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for research and pharmaceutical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and specifications can be aligned with customer requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.