Description

Phosphatidylcholine-L-α-Dipalmitoyl, [2-Palmitoyl-1-14C] is a high-purity, carbon-14 radiolabeled phospholipid essential for advanced metabolic and pharmacokinetic research. This compound matters because it provides a critical tracer for studying lipid metabolism, membrane dynamics, and drug delivery systems with high specificity and sensitivity. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and contract research organizations (CROs) focused on lipidomics, biomarker discovery, and the development of lipid-based therapeutics.

Application

• Tracer Studies in Lipid Metabolism: Used as a radiolabeled precursor to track the synthesis, turnover, and catabolism of phosphatidylcholine in biological systems.
• Drug Delivery & Formulation Research: Employed in the development and evaluation of liposomal and nanoparticle drug carriers to study encapsulation efficiency and in vivo distribution.
• Membrane Biophysics & Cell Biology: Serves as a tool to investigate phospholipid incorporation into cellular membranes, lipid raft formation, and signal transduction pathways.
• Preclinical ADME (Absorption, Distribution, Metabolism, Excretion): A vital tool for conducting quantitative mass balance and tissue distribution studies of lipid-based compounds in animal models.
• Biomarker Research: Facilitates the development of sensitive analytical methods (e.g., LC-MS/MS) for detecting and quantifying phosphatidylcholine species in complex biological samples.

Basic Information

Product Name	Phosphatidylcholine-L-α-Dipalmitoyl, [2-Palmitoyl-1-14C]
CAS No.	109971-57-5
Molecular Formula	C40H78NO8P * (14C labeled)
Molecular Weight	~734.0 g/mol (unlabeled)
Synonyms	1,2-Dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), [2-Palmitoyl-1-14C]; L-α-Phosphatidylcholine, dipalmitoyl-2-palmitoyl-1-14C; [1-14C]DPPC; Radiolabeled DPPC; 14C-DPPC; (R)-2,3-Bis(palmitoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate, 2-palmitoyl-1-14C
EINECS	Contact for details

Quality Control

Every batch of our radiolabeled phospholipids is manufactured and controlled under strict cGMP-like guidelines for research materials. Quality is assured through comprehensive analytical testing, including HPLC for radiochemical purity and chemical identity, and specific activity determination by liquid scintillation counting (LSC). A detailed Certificate of Analysis (COA), which includes batch-specific data on purity, specific activity, and solvent composition, is provided with each shipment to ensure full traceability and compliance with your research protocols.

Storage

Preserve in the original sealed container under an inert atmosphere at -20°C or below. This product is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Avoid repeated freeze-thaw cycles. For long-term storage, keep desiccated. Handle and dispose of in accordance with all applicable radiation safety regulations.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC)	Conforms to reference standard
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Chemical Purity (TLC/HPLC)	≥ 95%
Solvent (if supplied in solution)	Specified Chloroform, Ethanol, or Toluene/Ethanol mixture
Concentration (if supplied in solution)	~1.0 mCi/mL or as specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.