Description

2-(4-Bromophenyl)-2-Fluoroacetic Acid is a high-purity, synthetically valuable fluorinated aromatic building block. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for introducing both bromoaryl and α-fluoroacetate functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, leveraging the bioactivity of the fluorinated moiety.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials for enhanced stability and performance.
• Chemical Biology Probes: Useful for synthesizing fluorinated analogs of bioactive molecules for metabolic pathway studies and imaging.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis projects and scale-up services for clients in life sciences.

Basic Information

Product Name	2-(4-Bromophenyl)-2-Fluoroacetic Acid
CAS No.	109050-30-8
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	2-(4-Bromophenyl)-2-fluoroacetic acid; (4-Bromophenyl)fluoroacetic Acid; α-Fluoro-4-bromophenylacetic Acid; 2-Fluoro-2-(4-bromophenyl)acetic Acid; 4-Bromo-α-fluorophenylacetic Acid; p-Bromophenylfluoromethylcarboxylic Acid; 109050-30-8; 2-(p-Bromophenyl)-2-fluoroethanoic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Bromophenyl)-2-Fluoroacetic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and incompatible materials. Due to its acidic nature, handle with appropriate engineering controls and personal protective equipment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.