Description

Uridine Diphosphate Glucose, [Glucose-6-3H] is a high-specific-activity, tritium-labeled nucleotide sugar essential for studying glycosylation pathways. This compound serves as a critical tracer for the precise investigation of enzymatic activities in glucosyltransferase and glycogen synthase reactions. It is indispensable for researchers and manufacturers in pharmaceutical development, biochemical research, and metabolic disorder diagnostics who require reliable, high-purity radiolabeled substrates.

Application

• Enzyme Kinetics & Mechanism Studies: As a labeled substrate for glucosyltransferases, glycogen synthases, and other glycosyltransferases.
• Metabolic Pathway Tracing: To track and quantify the incorporation of glucose into glycogen, glycoproteins, and glycolipids in cell-based and in vitro assays.
• Drug Discovery & Screening: Used in high-throughput assays to identify and characterize inhibitors or activators of carbohydrate-metabolizing enzymes for therapeutic targets.
• Diagnostic Kit Development: A key component in the development of clinical diagnostic assays for metabolic disorders such as glycogen storage diseases.
• Biochemical Research: Fundamental research into carbohydrate metabolism, cell wall biosynthesis in plants and microbes, and post-translational modifications.
• Quality Control (QC) in Biologics: For monitoring glycosylation patterns and consistency in the production of therapeutic proteins and antibodies.

Basic Information

Product Name	Uridine Diphosphate Glucose, [Glucose-6-3H]
CAS No.	108866-91-7
Molecular Formula	C15H22N2O17P2 * (³H)
Molecular Weight	~568.3 g/mol (unlabeled)
Synonyms	UDP-[glucose-6-³H]; UDP-Glc-³H; UDP-α-D-[6-³H]Glucose; Uridine 5'-(α-D-[6-³H]glucopyranosyl diphosphate); [6-³H]UDP-Glucose; Tritiated UDP-Glucose; UDP-[6-³H]Glc; Uridine Diphospho[6-³H]glucose
EINECS	Contact for details

Quality Control

Every batch of our Uridine Diphosphate Glucose, [Glucose-6-3H] is manufactured and analyzed under stringent quality systems. We guarantee high radiochemical purity and specific activity to ensure reliable and reproducible results in sensitive assays. Our products undergo rigorous quality testing, including HPLC and spectroscopic analysis, to ensure compliance with research-grade standards. Certificates of Analysis (COA) detailing specific activity, purity, and solvent composition are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to prevent condensation. Store in accordance with local regulations for radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid or solution (as specified)
Identification (HPLC/MS)	Conforms to standard
Specific Activity	10-40 Ci/mmol (Contact for exact value)
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC)	≥ 90%
Solvent	Ethanol:Water mixture or as specified
Concentration	1 mCi/mL or as specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.