Description

Rociclovir CAS NO 108436-80-2 is a synthetic nucleoside analogue with significant antiviral activity. This compound is a key intermediate in the research and development of novel antiviral therapeutics, particularly those targeting herpesviruses and other DNA viruses. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions engaged in antiviral drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced antiviral active pharmaceutical ingredients (APIs).
• Antiviral Research: Used as a reference standard and precursor in biochemical and virological studies to investigate mechanisms of viral inhibition.
• Process Development: Serves as a key starting material (KSM) or intermediate in the scale-up and optimization of antiviral drug manufacturing processes.
• Analytical Standard: Employed for method development, validation, and quality control (HPLC, LC-MS) in pharmaceutical analysis.
• Medicinal Chemistry: Provides a core scaffold for the design and synthesis of new nucleoside analogue libraries for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Rociclovir
CAS No.	108436-80-2
Molecular Formula	C8H11N5O3
Molecular Weight	225.21 g/mol
Synonyms	9-[(1,3-Dihydroxy-2-propoxy)methyl]guanine; DHBG; 2-Amino-1,9-dihydro-9-[[1,3-dihydroxy-2-propoxy]methyl]-6H-purin-6-one; BIOLF-62; NSC 629153; Rociclovir (BIOLF-62); 1,9-Dihydro-9-[[1,3-dihydroxy-2-propoxy]methyl]-6H-purin-6-one, 2-amino-
EINECS	Contact for details

Quality Control

Our Rociclovir is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, HPLC), purity assay (HPLC), and control of specified impurities, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.