Description

Dl-Glutamic-2-13C Acid is a stable isotope-labeled analog of glutamic acid, where the carbon atom at the 2-position is enriched with the 13C isotope. This compound is essential as an internal standard and tracer in advanced analytical and metabolic research, enabling precise quantification and pathway elucidation. It is primarily utilized by research institutions, pharmaceutical developers, and analytical laboratories engaged in mass spectrometry, NMR spectroscopy, and metabolic flux analysis.

Application

• As an internal standard for the accurate quantification of glutamic acid in complex biological matrices using LC-MS or GC-MS.
• A metabolic tracer in in vitro and in vivo studies to investigate the Krebs cycle, amino acid metabolism, and neurotransmitter synthesis pathways.
• Use in NMR spectroscopy for structural analysis and dynamic studies of biochemical processes.
• Critical reagent in pharmaceutical research for drug metabolism and pharmacokinetics (DMPK) studies.
• Production of isotopically labeled peptides, proteins, or other biochemicals for research purposes.
• Quality control and method development in analytical chemistry laboratories to ensure accuracy and precision.

Basic Information

Product Name	Dl-Glutamic-2-13C Acid
CAS No.	108345-12-6
Molecular Formula	C413CH9NO4
Molecular Weight	148.11 g/mol (for 13C1 isotopologue)
Synonyms	(±)-2-Aminopentanedioic-2-13C Acid; DL-Glutamic-2-13C Acid; Glutamic Acid-2-13C (racemic); 2-13C-Glutamic Acid; (RS)-Glutamic-2-13C Acid; 13C Labeled Glutamic Acid; 2-Amino-2-13C-pentanedioic Acid; 13C1-Glutamic Acid
EINECS	Contact for details

Quality Control

Our Dl-Glutamic-2-13C Acid is produced under strict quality management protocols. Each batch is characterized to ensure high chemical purity and isotopic enrichment, with key parameters verified by techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) is provided, detailing assay, isotopic purity (atom % 13C), and impurity profiles to meet the exacting standards of research and analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant or inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Purity (atom % 13C)	≥ 99%
Chemical Purity	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.