Description

5-(2-Fluoroethyl)-2'-Fluoroarabinofuranosyluracil is a fluorinated nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel antiviral and anticancer therapeutics. It is primarily required by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in cutting-edge drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of next-generation antiviral medications.
• Anticancer Drug Research: Investigated as a potential active component or prodrug in oncology research targeting specific cellular pathways.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand nucleoside metabolism and related biological processes.
• Radiopharmaceutical Precursor: Potential use as a precursor for the development of fluorinated tracers in Positron Emission Tomography (PET) imaging agents.
• Nucleoside Analog Development: A reference standard in the research and development of modified nucleosides with enhanced therapeutic profiles.

Basic Information

Product Name	5-(2-Fluoroethyl)-2'-Fluoroarabinofuranosyluracil
CAS No.	108008-64-6
Molecular Formula	C11H14F2N2O6
Molecular Weight	308.24 g/mol
Synonyms	2'-Fluoro-5-(2-fluoroethyl)arabinofuranosyluracil; 1-((2R,3S,4S,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(2-fluoroethyl)pyrimidine-2,4(1H,3H)-dione; 5-(2-Fluoroethyl)-2'-fluoro-1-β-D-arabinofuranosyluracil; FEAU; 2'-F-5-(2-Fluoroethyl) Ara-U; 108008-64-6
EINECS	Contact for details

Quality Control

Our production of 5-(2-Fluoroethyl)-2'-Fluoroarabinofuranosyluracil adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.