Description

(2R,2'R)-2,2'-Bipyrrolidine is a high-purity, chiral bidentate ligand and building block of significant importance in asymmetric synthesis. Its rigid, C2-symmetric structure makes it a valuable catalyst component for creating enantiomerically pure compounds, which are critical in advanced pharmaceutical development. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and complex molecular architectures.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metals (e.g., ruthenium, iridium, palladium) in enantioselective hydrogenation, C-C bond formation, and other catalytic transformations.
• Pharmaceutical Intermediates: A key building block in the synthesis of chiral active pharmaceutical ingredients (APIs) and complex natural product analogs.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science: Employed in the synthesis of chiral polymers and advanced organic frameworks with specific optical properties.
• Academic & Industrial R&D: A fundamental tool for methodological development in organic chemistry and process chemistry laboratories.

Basic Information

Product Name	(2R,2'R)-2,2'-Bipyrrolidine
CAS No.	107886-22-6
Molecular Formula	C8H16N2
Molecular Weight	140.23 g/mol
Synonyms	(R,R)-2,2'-Bipyrrolidine; (2R,2'R)-2,2'-Bipyrrolidine; (R,R)-2,2'-Bipyrrolidine; (R,R)-2,2'-DIPYRROLIDINE; (R,R)-2,2'-BIPYRROLIDINE; (R,R)-2,2'-Bipyrrolidine; (R,R)-2,2'-Bipyrrolidine; (R,R)-2,2'-Bipyrrolidine
EINECS	Contact for details

Quality Control

Every batch of (2R,2'R)-2,2'-Bipyrrolidine is produced and tested under a strict quality management system. We ensure high enantiomeric excess (ee) and chemical purity through advanced analytical techniques, including chiral HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to guarantee consistency and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize oxidation and moisture absorption. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.