Description

Cevimeline Hydrochloride is a high-purity pharmaceutical active ingredient, specifically the hydrochloride salt of cevimeline. This compound is a cholinergic agonist of significant importance in advanced therapeutic applications, valued for its precise pharmacological activity. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of prescription medications.

Application

• Active Pharmaceutical Ingredient (API) in the manufacture of prescription drugs.
• Pharmacological Research as a reference standard or investigational compound in studies of cholinergic systems.
• Formulation Development for solid dosage forms such as tablets and capsules.
• Quality Control Laboratories for use as an analytical reference standard in HPLC and other methods.
• Preclinical and Clinical Trial Material for drug development programs.

Basic Information

Product Name	Cevimeline Hydrochloride
CAS No.	107233-08-9
Molecular Formula	C10H17NOS•HCl
Molecular Weight	219.77 g/mol (Free base: 183.31 g/mol)
Synonyms	Cevimeline HCl; (2R,3R)-3-(2(S)-1-Methyl-2-pyrrolidinyl)ethyl-2-phenylthiazolidine-4-one Hydrochloride; SNI-2011; AF102B; Evoxac (Brand Name); Sporalon
EINECS	Contact for details

Quality Control

Our Cevimeline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and strength, consistent with ICH guidelines. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters is provided with every shipment to ensure full traceability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.