Description

5-Fluoro-2',3'-Dideoxycytidine is a fluorinated nucleoside analog with significant research and pharmaceutical development potential. This compound matters as a key synthetic intermediate and active pharmaceutical ingredient (API) in the development of antiviral and anticancer therapeutics. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in nucleoside chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral and antineoplastic (anticancer) nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate metabolic pathways and mechanisms of action.
• Antiviral Agent Development: Investigated for its potential activity against retroviruses and other viral families due to its modified sugar moiety.
• Anticancer Drug Research: Explored in preclinical studies for its ability to interfere with DNA synthesis in rapidly dividing cancer cells.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial production of related active pharmaceutical ingredients (APIs).

Basic Information

Product Name	5-Fluoro-2',3'-Dideoxycytidine
CAS No.	107036-62-4
Molecular Formula	C9H12FN3O3
Molecular Weight	229.21 g/mol
Synonyms	5-Fluoro-ddC; 5-Fluoro-2',3'-dideoxycytidine; 1-((2R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione; 5-Fluoro-2',3'-dideoxycytidine; 5-F-ddC; 2',3'-Dideoxy-5-fluorocytidine; 5-Fluoro-2',3'-dideoxycytidine (5-F-ddC); 5-Fluoro-2',3'-dideoxycytidine, 5-F-ddC
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2',3'-Dideoxycytidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Purity (HPLC)	≥98.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.