Description

Tetraethylammonium Bromide, [Ethyl-1-14C] CAS NO 106872-81-5 is a carbon-14 labeled isotopologue of the classic quaternary ammonium salt, tetraethylammonium bromide. This radiolabeled compound is a critical tool for advanced research, enabling precise metabolic and pharmacokinetic studies through its radioactive tracer properties. It is essential for scientists in pharmaceutical development, biochemistry, and analytical chemistry who require high-specific-activity materials for autoradiography, ADME (Absorption, Distribution, Metabolism, and Excretion) studies, and mechanistic pathway elucidation.

Application

• Pharmacokinetic and ADME Studies: Used as a radiolabeled tracer to investigate the absorption, distribution, metabolism, and excretion of quaternary ammonium compounds and related pharmaceuticals.
• Metabolic Pathway Analysis: Enables the tracking and identification of metabolic products in biological systems for biochemical research.
• Analytical Method Development: Serves as an internal standard or reference compound in advanced analytical techniques like Liquid Chromatography-Mass Spectrometry (LC-MS) for quantitative bioanalysis.
• Neurological and Ion Channel Research: Acts as a labeled analog of the potassium channel blocker tetraethylammonium (TEA) for studying receptor binding and channel function.
• Environmental Fate Studies: Employed in research to trace the environmental degradation and movement of chemical entities.
• Chemical Synthesis Intermediate: Utilized in the synthesis of more complex carbon-14 labeled molecules for research purposes.

Basic Information

Item	Details
Product Name	Tetraethylammonium Bromide, [Ethyl-1-14C]
CAS No.	106872-81-5
Molecular Formula	C8H2014CNBr
Molecular Weight	Contact for details
Synonyms	TEA-Br-14C; [1-14C]Ethyltriethylammonium Bromide; N,N,N-Triethyl(1-14C)ethanaminium Bromide; 14C-Labeled Tetraethylammonium Bromide; TETRAETHYLAMMONIUM BROMIDE (ETHYL-1-14C); (1-14C)Ethyltriethylammonium bromide; TEAB-14C; Radiolabeled TEAB
EINECS	Contact for details

Quality Control

Every batch of our carbon-14 labeled Tetraethylammonium Bromide is produced and tested under stringent conditions to ensure the highest standards of radiochemical purity, chemical purity, and specific activity. Our quality protocols are designed to meet the exacting requirements of research and regulatory applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing parameters such as radiochemical purity (by HPLC), specific activity, chemical purity, and solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a controlled environment to minimize exposure to atmospheric moisture. For long-term storage, consider conditions recommended for radioactive materials. Keep away from incompatible substances.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	Contact for details (mCi/mmol)
Solvent Content (Residual Solvents)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.