Description

Ethyl 2-Fluoro-3-Hydroxybenzoate is a valuable fluorinated aromatic ester building block, distinguished by its hydroxy and fluoro substituents which impart unique reactivity and physical properties. This compound is essential for advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals where fluorine incorporation is a key strategy for modulating bioactivity and metabolic stability. It serves as a critical intermediate for researchers and manufacturers in fine chemical, pharmaceutical R&D, and material science industries seeking to introduce specific fluorinated motifs into complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) with fluorinated aromatic cores, potentially for anti-inflammatory, antimicrobial, or CNS-targeting drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances lipophilicity and biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated organic compounds used in electronic displays and organic light-emitting diodes.
• Polymer Modification: Acts as a monomer or modifier for creating specialty polymers with improved chemical resistance, thermal stability, or specific optical properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new fluorination reactions and constructing complex heterocyclic systems.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	Ethyl 2-Fluoro-3-Hydroxybenzoate
CAS No.	105836-28-0
Molecular Formula	C9H9FO3
Molecular Weight	184.16 g/mol
Synonyms	2-Fluoro-3-hydroxybenzoic acid ethyl ester; Ethyl 2-fluoro-3-hydroxybenzoate; Benzoic acid, 2-fluoro-3-hydroxy-, ethyl ester; 3-Hydroxy-2-fluorobenzoic acid ethyl ester; Ethyl 3-hydroxy-2-fluorobenzoate; 2-Fluoro-3-hydroxy-benzoic acid ethyl ester; Ethyl 2-fluoro-3-hydroxybenzenecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Fluoro-3-Hydroxybenzoate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.