Description

Rivastigmine CAS NO 105601-20-5 is a potent and selective carbamate-based acetylcholinesterase inhibitor. This compound is of critical importance in the pharmaceutical industry for the development of treatments for neurodegenerative disorders. It is primarily required by manufacturers of active pharmaceutical ingredients (APIs) and finished dosage forms targeting cognitive decline.

Application

• Active Pharmaceutical Ingredient (API): Primary use in the formulation of prescription medications for Alzheimer's disease and dementia associated with Parkinson's disease.
• Neurological Research: A key reference standard and tool compound in preclinical studies investigating cholinergic pathways and cognitive function.
• Transdermal Patch Formulations: Used in the production of innovative, sustained-release patch delivery systems to improve patient compliance.
• Oral Solid Dosage Forms: A core component in the manufacture of capsules and tablets for the management of mild to moderate dementia.
• Chemical Intermediate: Serves as a crucial synthetic building block for the preparation of related cholinesterase inhibitor analogs.
• Analytical Standard: Employed as a high-purity calibrant in quality control (QC) and quality assurance (QA) laboratories for HPLC and related assays.

Basic Information

Product Name	Rivastigmine
CAS No.	105601-20-5
Molecular Formula	C14H22N2O2
Molecular Weight	250.34 g/mol
Synonyms	(S)-3-[1-(Dimethylamino)ethyl]phenyl N-ethyl-N-methylcarbamate; Exelon; SDZ ENA 713; ENA-713; Rivastigmine Tartrate (salt form); Rivastigmin; Rivastigmina; Rivastigminum
EINECS	Contact for details

Quality Control

Our Rivastigmine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for pharmaceutical use, including identity, purity, and impurity profiles. Certificates of Analysis (COA) compliant with current pharmacopeial standards (e.g., USP, EP) are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.