Description

3,5-Difluoro-4-Methoxycinnamic Acid is a high-purity fluorinated cinnamic acid derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its value lies in the unique reactivity imparted by the difluoro and methoxy substituents, enabling precise molecular construction for complex target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging its fluorinated aromatic structure.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated mesogens and electron-transport materials in display and lighting technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Heck, Suzuki) and as a precursor for other fluorinated fine chemicals.
• Biochemical Research: Used as a probe or substrate in enzymatic studies due to its specific substitution pattern.
• Polymer Modification: Serves as a monomer or additive to introduce fluorinated aromatic groups into polymer chains, altering material properties.

Basic Information

Product Name	3,5-Difluoro-4-Methoxycinnamic Acid
CAS No.	105219-43-0
Molecular Formula	C10H8F2O3
Molecular Weight	214.17 g/mol
Synonyms	(E)-3-(3,5-Difluoro-4-methoxyphenyl)acrylic acid; 3,5-Difluoro-4-methoxycinnamate; 2-Propenoic acid, 3-(3,5-difluoro-4-methoxyphenyl)-, (2E)-; 3,5-Difluoro-4-methoxy-trans-cinnamic acid; 3-(3,5-Difluoro-4-methoxyphenyl)-2-propenoic acid; DFMCA; 4-Methoxy-3,5-difluorocinnamic acid
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-Methoxycinnamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.