Description

(-)-Eseroline Fumarate CAS NO 104015-29-4 is a high-purity, enantiomerically pure salt form of the alkaloid derivative eseroline. This compound is a critical intermediate and reference standard in advanced pharmaceutical research and development, particularly for studies involving acetylcholinesterase activity and neurological pathways. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors requiring precise and reliable chiral building blocks.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of complex active pharmaceutical ingredients (APIs) targeting neurological disorders.
• Biochemical Research: Used as a reference standard and tool compound in studies of acetylcholinesterase inhibition, cholinergic neurotransmission, and related enzymatic assays.
• Analytical Standard: Employed for method development, calibration, and quality control in HPLC, LC-MS, and other analytical techniques within QC/QA laboratories.
• Neuroscience Research: Utilized in vitro and in vivo research models to investigate mechanisms related to Alzheimer's disease, myasthenia gravis, and other conditions affecting the cholinergic system.
• Fine Chemical Synthesis: Acts as a specialized building block for the preparation of novel analogs and derivatives in medicinal chemistry programs.

Basic Information

Product Name	(-)-Eseroline Fumarate
CAS No.	104015-29-4
Molecular Formula	C15H21N3O2 • C4H4O4
Molecular Weight	403.42 g/mol
Synonyms	(-)-Eseroline hydrogen fumarate; (3aS,8aR)-2,3,3a,8a-Tetrahydro-1H-pyrrolo[2,3-b]indol-5-ol fumarate; Eseroline fumarate salt; Physostigmine metabolite fumarate; 1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-ol fumarate
EINECS	Contact for details

Quality Control

Our (-)-Eseroline Fumarate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.