Description

2'-Iodospiperone is a high-purity iodinated derivative of the butyrophenone class, serving as a critical intermediate and reference standard in advanced pharmaceutical research and development. Its primary value lies in its utility for studying and developing novel dopamine receptor ligands, particularly for neurological and psychiatric applications. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors who require precise, well-characterized building blocks for drug discovery programs.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of novel antipsychotic and neuroleptic agents targeting dopamine receptors.
• Biochemical Research: Used as a reference standard and tracer compound in receptor binding assays and pharmacological studies to investigate dopamine D2 receptor interactions.
• Radiopharmaceutical Development: Serves as a precursor molecule for the synthesis of radioiodinated analogs used in positron emission tomography (PET) imaging and diagnostic applications.
• Fine Chemical Synthesis: A specialized building block for constructing complex molecules in medicinal chemistry and custom synthesis projects.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies on neurotransmission and central nervous system (CNS) drug mechanisms.

Basic Information

Product Name	2'-Iodospiperone
CAS No.	103445-60-9
Molecular Formula	C23H26FIN2O2
Molecular Weight	508.37 g/mol
Synonyms	2'-Iodospiperone; 8-[4-(4-Fluorophenyl)-4-oxobutyl]-1-(2-iodophenyl)-1,3,8-triazaspiro[4.5]decan-4-one; 1-(2-Iodophenyl)-4-[4-(4-fluorophenyl)-4-oxobutyl]piperazin-2-one; Iodospiperone (2'-isomer); Spiperone, 2'-iodo-
EINECS	Contact for details

Quality Control

Our 2'-Iodospiperone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed in a dry, inert atmosphere to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.