Description

Tiviciclovir is a potent antiviral nucleoside analogue with significant therapeutic potential. This compound is a key intermediate in the synthesis of advanced antiviral pharmaceuticals, offering a critical building block for research and development. It is primarily utilized by pharmaceutical manufacturers, biotechnology research institutions, and contract development and manufacturing organizations (CDMOs) engaged in the development of novel antiviral agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of next-generation antiviral drugs targeting herpesviruses and other DNA viruses.
• Antiviral Research & Development: Used as a reference standard and active material in preclinical studies to evaluate efficacy, pharmacokinetics, and mechanism of action.
• Process Chemistry: Employed in route scouting, optimization, and scale-up activities for the commercial production of antiviral active pharmaceutical ingredients (APIs).
• Biochemical Studies: Utilized in enzymatic and cellular assays to study viral replication inhibition and resistance mechanisms.
• Custom Synthesis: A starting point for the development of prodrugs or structurally modified analogues with improved pharmacological profiles.

Basic Information

Product Name	Tiviciclovir
CAS No.	103024-93-7
Molecular Formula	C10H13N5O4
Molecular Weight	267.24 g/mol
Synonyms	2-Amino-9-[[(1,3-Dihydroxy-2-propoxy)methyl]guanine; DHBG; 9-[[(1,3-Dihydroxy-2-propoxy)methyl]guanine; 2-Amino-1,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one; BMS-224791; Tiviciclovir Intermediate; Acyclovir Analog
EINECS	Contact for details

Quality Control

Our Tiviciclovir is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.