Description

12-Hydroperoxy-5,8,11,14,17-Eicosapentaenoic Acid is a specialized bioactive lipid peroxide derived from eicosapentaenoic acid (EPA). This compound serves as a critical intermediate and research tool in the study of lipid peroxidation pathways and cellular signaling mechanisms. It is essential for researchers and manufacturers in the pharmaceutical, nutraceutical, and life science industries focused on inflammation, oxidative stress, and metabolic research.

Application

• Biochemical Research: Used as a reference standard and key intermediate in studying the lipoxygenase (LOX) pathway and the biosynthesis of specialized pro-resolving mediators (SPMs).
• Pharmaceutical Development: Investigated for its role in inflammatory and oxidative stress pathways, aiding in the discovery of novel therapeutic agents.
• Nutraceutical Analysis: Employed as an analytical standard to assess the oxidation products and stability of ω-3 fatty acid supplements like EPA.
• Cell Signaling Studies: Utilized to explore its effects on cellular functions, including gene expression and enzyme activity related to inflammation.
• Cosmeceutical Research: Investigated for potential applications in skin care formulations targeting oxidative damage.
• Food Science: Serves as a marker for lipid oxidation in fortified foods and oils containing polyunsaturated fatty acids.

Basic Information

Product Name	12-Hydroperoxy-5,8,11,14,17-Eicosapentaenoic Acid
CAS No.	101973-23-3
Molecular Formula	C₂₀H₃₂O₄
Molecular Weight	336.47 g/mol
Synonyms	12-HpEPE; 12(S)-HPEPE; 12(S)-Hydroperoxyeicosapentaenoic acid; 12-Hydroperoxy-5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid; 12(S)-HpEPE; 12-HPEPE; 12-Hydroperoxy-EPA; 12(S)-Hydroperoxy-5,8,11,14,17-eicosapentaenoic acid
EINECS	Contact for details

Quality Control

Our 12-Hydroperoxy-5,8,11,14,17-Eicosapentaenoic Acid is produced under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for analytical reagents, ensuring reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize degradation. This product is easily oxidized and light-sensitive; prolonged exposure to air, light, or elevated temperatures should be avoided. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.