Description

D-Glucose (3-13C) CAS NO 101615-88-7 is a stable isotope-labeled analog of D-glucose, where the carbon atom at the 3-position is enriched with the non-radioactive carbon-13 isotope. This compound is an essential tool for advanced metabolic research, enabling precise tracking and quantification of glucose utilization and metabolic flux in biological systems. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in tracer studies, NMR spectroscopy, and mass spectrometry.

Application

• Metabolic Flux Analysis (MFA): Used as a 13C-labeled tracer to map intracellular metabolic pathways and quantify reaction rates in cell cultures, tissues, and whole organisms.
• NMR Spectroscopy: Serves as a critical substrate for 13C-NMR studies to investigate carbohydrate metabolism, enzyme mechanisms, and structural dynamics.
• Mass Spectrometry (MS): Employed in LC-MS and GC-MS platforms as an internal standard for the accurate quantification of glucose and its metabolites, enhancing data precision.
• Drug Development & Pharmacokinetics: Facilitates studies on how new therapeutic agents affect glucose metabolism, absorption, and distribution.
• Nutritional & Biomedical Research: Applied in studies of diabetes, cancer metabolism, and other metabolic disorders to understand dysregulated energy pathways.
• Biochemical Reagent Manufacturing: Incorporated into the production of specialized kits, assays, and diagnostic reagents for research and clinical use.

Basic Information

Product Name	D-Glucose (3-13C)
CAS No.	101615-88-7
Molecular Formula	C6H12O6 (with 13C at position 3)
Molecular Weight	~181.15 g/mol (for 13C1 labeled)
Synonyms	D-[3-13C]Glucose; [3-13C]-D-Glucose; D-Glucose-3-13C; (3-13C)Glucose; D-Glucose (3-13C); Glucose-3-13C; Dextrose-3-13C; 3-13C-Labeled D-Glucose
EINECS	Contact for details

Quality Control

Our D-Glucose (3-13C) is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and isotopic enrichment. Certificates of Analysis (COA) are provided, detailing specifications for isotopic purity, chemical purity (by HPLC), and the absence of biological contaminants. We support compliance with relevant research and manufacturing standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98% (Chemical Purity)
Isotopic Enrichment	≥ 99 atom % 13C
Isotopic Purity (NMR/MS)	≥ 98% at position 3
Water Content (KF)	≤ 1.0%
Specific Rotation	+52.5° to +53.0° (c=10, H2O)
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.