Description

L-Aspartic Acid (1,4-13C2) is a stable isotope-labeled analog of the essential amino acid L-aspartic acid, specifically enriched with carbon-13 at the 1 and 4 positions. This high-purity labeled compound is critical for advanced research requiring precise metabolic pathway tracing and quantification. It is primarily utilized by scientists and manufacturers in the fields of pharmaceutical research, metabolic studies, and analytical chemistry for applications such as NMR spectroscopy and mass spectrometry.

Application

• Metabolic Flux Analysis (MFA): As a key tracer for studying the citric acid cycle and amino acid metabolism in biological systems.
• Biomedical & Pharmaceutical Research: Used in the development and testing of new drugs, particularly those targeting metabolic disorders or requiring detailed pharmacokinetic studies.
• Proteomics & Stable Isotope Labeling by Amino acids in Cell culture (SILAC): Enables accurate quantification of protein expression and turnover rates.
• NMR Spectroscopy: Serves as an internal standard or reference compound due to its distinct 13C signature, enhancing spectral clarity and data accuracy.
• Mass Spectrometry (MS): Used as an internal standard for the precise quantification of aspartic acid and related metabolites in complex samples via LC-MS or GC-MS.
• Nutritional Science Research: Investigates amino acid utilization, protein synthesis, and metabolic pathways in nutritional studies.

Basic Information

Item	Detail
Product Name	L-Aspartic Acid (1,4-13C2)
CAS No.	101247-29-4
Molecular Formula	C413C2H7NO4
Molecular Weight	135.09 g/mol (for 13C2 labeled form)
Synonyms	(2S)-2-Aminobutanedioic-1,4-13C2 acid; L-Aspartic-1,4-13C2 acid; (S)-Aminosuccinic-1,4-13C2 acid; Aspartic Acid U-13C2 (1,4); L-13C2-Aspartic Acid; 13C Labeled L-Aspartic Acid; Aminosuccinic Acid-1,4-13C2
EINECS	Contact for details

Quality Control

Our L-Aspartic Acid (1,4-13C2) is manufactured under strict quality control protocols to ensure exceptional isotopic and chemical purity, suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity, and chiral purity. We adhere to high standards to guarantee reproducibility and reliability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment	≥ 99 atom % 13C (1,4 positions)
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Optical Rotation	[α]20/D: +24.5° to +26.0° (c=1 in 6N HCl)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.