Description

Eptastigmine CAS NO 101246-68-8 is a synthetic carbamate derivative and a centrally acting acetylcholinesterase inhibitor. This compound is of significant interest for its potential therapeutic applications in neurological research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on neuropharmacology.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the development of treatments for cognitive disorders.
• Neurological Disorder Studies: Used in preclinical and clinical research targeting conditions such as Alzheimer's disease and other forms of dementia.
• Acetylcholinesterase Inhibition Studies: Employed as a reference standard or tool compound in biochemical assays to study enzyme kinetics and inhibition mechanisms.
• Fine Chemical Synthesis: Acts as a critical building block for the synthesis of more complex carbamate-based molecules with potential biological activity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related pharmaceutical products.

Basic Information

Product Name	Eptastigmine
CAS No.	101246-68-8
Molecular Formula	C15H22N2O2S
Molecular Weight	294.42 g/mol
Synonyms	Eptastigmine; Heptylphysostigmine; MF-201; (3aS-cis)-1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-yl heptylcarbamate; Heptastigmine; L-693,487; PYRROLIDINE, 1-[(PHENYLMETHOXY)METHYL]-2-[(PHENYLMETHYL)THIO]-
EINECS	Contact for details

Quality Control

Our Eptastigmine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) documenting full specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.