Description

(R)-Fluoxetine is the single enantiomer form of the widely used selective serotonin reuptake inhibitor (SSRI). This specific stereoisomer is of significant interest in pharmaceutical research and development for studying structure-activity relationships and developing novel therapeutic agents. It is a critical chiral intermediate and reference standard for analytical and synthetic chemistry. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors focused on neuropharmacology and chiral drug development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the research and synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Used for method development, validation, and quality control (QC) testing in HPLC, GC, and other chromatographic assays.
• Metabolite Studies: Employed in pharmacological and toxicological research to investigate metabolic pathways and enantioselective biotransformations.
• Chiral Catalyst & Ligand Research: Acts as a precursor or model compound in the development of asymmetric synthesis methodologies.
• Academic & Institutional Research: Utilized in universities and R&D labs for fundamental studies in medicinal chemistry and neuropharmacology.
• Impurity Profiling: Critical for identifying and quantifying stereoisomeric impurities in bulk (R,S)-Fluoxetine and related formulations.

Basic Information

Product Name	(R)-Fluoxetine
CAS No.	100568-03-4
Molecular Formula	C17H18F3NO
Molecular Weight	309.33 g/mol
Synonyms	(R)-Fluoxetine; (R)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine; (R)-N-Methyl-3-phenyl-3-(α,α,α-trifluoro-p-tolyloxy)propylamine; (R)-Prozac; (R)-Lilly 110140; (3R)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine; (R)-Fluoxetine Hydrochloride (salt form precursor)
EINECS	Contact for details

Quality Control

Our (R)-Fluoxetine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.