Description

Propanol-N, [1-3H] is a tritium-labeled isotopologue of 1-propanol, specifically labeled at the 1-position. This compound is a critical tool for researchers requiring a radioactive tracer with high specific activity for metabolic and pharmacokinetic studies. It is primarily utilized in the pharmaceutical, biotechnology, and agrochemical research sectors for advanced analytical applications such as radioligand binding assays, autoradiography, and ADME (Absorption, Distribution, Metabolism, and Excretion) investigations. Its high volatility necessitates careful handling and specialized storage conditions to maintain isotopic integrity and safety.

Application

• Metabolic Pathway Tracing: Used as a radioactive tracer to study the metabolic fate of propanol and related compounds in biological systems.
• Pharmacokinetic Studies (ADME): Essential for quantifying the absorption, distribution, metabolism, and excretion of new chemical entities in drug discovery and development.
• Biochemical Research: Serves as a labeled precursor or intermediate in the synthesis of more complex tritiated molecules for receptor binding studies.
• Environmental Science: Applied in research to track the environmental degradation and movement of short-chain alcohols.
• Analytical Method Development: Used as an internal standard or tracer in advanced chromatographic and mass spectrometric techniques to improve detection limits and accuracy.
• Material Science Research: Investigates surface interactions, polymerization kinetics, and solvent behavior in labeled form.

Basic Information

Product Name	Propanol-N, [1-3H]
CAS No.	19986-23-3
Molecular Formula	C3H7TOH or C3H73HOH
Molecular Weight	~62.10 g/mol (varies with specific activity)
Synonyms	1-Propanol-1-t; Tritiated 1-Propanol; [1-3H]Propan-1-ol; n-Propanol-1-t; 1-Hydroxypropane-1-t; Propyl alcohol-1-t; Propanol-1-3H; Tritium-labeled n-propanol
EINECS	Contact for details

Quality Control

Every batch of Propanol-N, [1-3H] is manufactured and analyzed under strict quality systems. Radiochemical purity and specific activity are critically assessed using validated methods such as radio-HPLC and liquid scintillation counting to ensure product integrity for sensitive research applications. A comprehensive Certificate of Analysis (COA) detailing specific activity, purity, solvent, and analytical methods is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended cold temperatures (e.g., 2-8°C or as specified on the label) to minimize radiolytic decomposition and volatility. Store in accordance with all local, national, and international regulations for radioactive materials.

Specification

Item	Specification
Appearance	Clear, colorless solution
Identification (IR/NMR)	Conforms to structure
Specific Activity	Customizable (Ci/mmol or GBq/mmol)
Radiochemical Purity (HPLC)	≥ 95% to ≥ 98%
Chemical Purity (GC)	≥ 98%
Solvent	Ethanol, Toluene, or as specified
Concentration	1 mCi/mL, or as customized

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.