Description

Trazodone CAS NO 19794-93-5 is a synthetic compound belonging to the class of serotonin antagonist and reuptake inhibitors (SARIs). This active pharmaceutical ingredient (API) is critical for the formulation of antidepressant medications, offering a distinct mechanism of action. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of central nervous system (CNS) therapeutics.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of antidepressant tablets and capsules.
• Generic Drug Formulation: Sourcing for the production of bioequivalent generic versions of trazodone hydrochloride medications.
• Clinical Research: Utilization as a reference standard or investigational material in pharmacological and neurochemical studies.
• Veterinary Medicine: Potential application in veterinary behavior modification therapies under professional guidance.
• Analytical Testing: Serves as a high-purity standard for quality control laboratories performing HPLC, LC-MS, or spectroscopic assays.

Basic Information

Item	Detail
Product Name	Trazodone
CAS No.	19794-93-5
Molecular Formula	C19H22ClN5O
Molecular Weight	371.86 g/mol
Synonyms	2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one; Trazodone Base; AF-1161; TRZ; Trazolan; Trittico; Desyrel; Molipaxin; Thombran; Trazorel
EINECS	243-323-0

Quality Control

Our Trazodone is manufactured and tested under a strict quality management system. We ensure compliance with ICH guidelines and relevant pharmacopeial standards (e.g., USP, EP) for identity, purity, and strength. A comprehensive Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and heavy metals is provided with each batch to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 2.0%
Loss on Drying	NMT 1.0%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.