Description

L-Alanine-Ul-14C is a uniformly carbon-14 labeled isotopologue of the essential amino acid L-alanine, identified by CAS NO 18875-37-1. This radiolabeled compound is a critical tool for metabolic pathway tracing, pharmacokinetic studies, and biochemical research, offering unparalleled insight into biological processes. It is primarily utilized by pharmaceutical R&D teams, contract research organizations (CROs), and academic institutions conducting advanced tracer studies and drug development.

Application

• Metabolic Pathway Analysis: Used as a tracer to study amino acid metabolism, gluconeogenesis, and protein synthesis in vivo and in vitro.
• Drug Metabolism and Pharmacokinetics (DMPK): Essential for tracking the absorption, distribution, metabolism, and excretion (ADME) of new chemical entities in preclinical studies.
• Biochemical Research: Serves as a labeled precursor in enzymatic studies and the investigation of metabolic disorders.
• Agricultural Chemistry: Applied in research on plant amino acid metabolism and nutrient uptake studies.
• Medical Diagnostics Development: Used in the research and development of novel diagnostic agents and imaging probes.
• Quality Control Reference Standard: Acts as an internal standard in advanced analytical methods like LC-MS for accurate quantification.

Basic Information

Item	Detail
Product Name	L-Alanine-Ul-14C
CAS No.	18875-37-1
Molecular Formula	C3H714CNO2
Molecular Weight	~92.1 g/mol (based on 14C)
Synonyms	(S)-2-Aminopropionic acid-U-14C; L-α-Aminopropionic acid-U-14C; (S)-Alanine-U-14C; Uniformly Labeled L-Alanine-14C; L-Alanine (U-14C); Ala-U-14C; 14C-L-Alanine
EINECS	Contact for details

Quality Control

Every batch of L-Alanine-Ul-14C is manufactured and analyzed under strict quality systems. We provide comprehensive analytical data including radiochemical purity (typically >98% by HPLC), specific activity, and chemical identity confirmation. Certificates of Analysis (COA) detailing all specifications and test results are supplied with each shipment to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Radiochemical Purity (HPLC)	≥ 98%
Specific Activity	Customizable (e.g., 50-60 mCi/mmol)
Chemical Purity (HPLC)	≥ 95%
Solvent (if supplied in solution)	Specified on COA (e.g., Ethanol:Water)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.