Description

α-Neu5Ac-[2->8]-α-Neu5Ac-[2->3]-β-D-Gal-[1->4]-D-Glc Sodium Salt is a defined, high-purity oligosaccharide derivative of sialic acid, supplied as a sodium salt for enhanced stability and solubility. This compound is a critical reference standard and building block for advanced glycobiology research and biopharmaceutical development. It is essential for scientists and manufacturers in the fields of vaccinology, therapeutic antibody engineering, and diagnostic assay development, where precise glycan structures are required to study biological interactions and ensure product quality.

Application

• Glycobiology Research: As a defined glycan standard for studying sialic acid linkages, cell-cell recognition, and pathogen-host interactions.
• Vaccine Development: For the research and quality control of conjugate vaccines targeting bacterial capsular polysaccharides containing sialic acid motifs.
• Biopharmaceutical Analysis: Used as a critical reference material in the characterization of glycosylation patterns on monoclonal antibodies and other therapeutic proteins.
• Diagnostic Reagent Manufacturing: Serves as a key component or calibrator in immunoassays and lectin-based detection kits targeting specific glycan epitopes.
• Enzymology Studies: A substrate for sialidases (neuraminidases) and sialyltransferases to investigate enzyme specificity and kinetics.
• Drug Discovery: Used in screening platforms to identify inhibitors of glycan-binding proteins involved in inflammation and cancer metastasis.

Basic Information

Item	Detail
Product Name	α-Neu5Ac-[2->8]-α-Neu5Ac-[2->3]-β-D-Gal-[1->4]-D-Glc Sodium Salt
CAS No.	18409-15-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Disialyl Lactose Sodium Salt; Neu5Acα2-8Neu5Acα2-3Galβ1-4Glc Sodium Salt; α-Neu5Ac-(2→8)-α-Neu5Ac-(2→3)-β-D-Gal-(1→4)-D-Glc Sodium Salt; DSL Sodium Salt; Disialyllactose, Sodium Salt; 3'-Sialyl-3-sialyllactose Sodium Salt; Oligosaccharide Derivative (Sialic Acid); Glycan Standard (Disialylated)
EINECS	Contact for details

Quality Control

Every batch of our α-Neu5Ac-[2->8]-α-Neu5Ac-[2->3]-β-D-Gal-[1->4]-D-Glc Sodium Salt is produced and tested under stringent quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development applications. A Certificate of Analysis (COA) detailing specifications such as purity (by HPLC), identity (by NMR/MS), and moisture content is available with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake. For long-term storage, consider desiccant or under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.