Description

Clomipramine Hydrochloride is a high-purity pharmaceutical active ingredient, a tricyclic antidepressant (TCA) compound essential for the development and manufacturing of critical neuropsychiatric medications. Its primary commercial value lies in its proven efficacy in managing obsessive-compulsive disorder (OCD) and major depressive disorder, making it a vital component in the global pharmaceutical supply chain. This product is specifically targeted at pharmaceutical manufacturers, research institutions, and compounding facilities requiring a reliable, high-quality API for formulation, clinical research, and generic drug production.

Application

• Pharmaceutical API: Primary active ingredient in the manufacture of antidepressant and anti-obsessive-compulsive medications.
• Generic Drug Formulation: Used in the production of generic versions of branded clomipramine hydrochloride tablets and capsules.
• Clinical Research & Development: Serves as a reference standard and raw material in preclinical and clinical studies for new CNS drug formulations.
• Compounding Pharmacy: Utilized by specialized pharmacies for preparing customized dosage forms for specific patient needs.
• Biochemical Research: Employed in neuroscience research to study serotonin and norepinephrine reuptake inhibition mechanisms.
• Veterinary Medicine: Investigational and therapeutic use in veterinary practices for behavioral disorders in animals.

Basic Information

Product Name	Clomipramine Hydrochloride
CAS No.	17321-77-6
Molecular Formula	C19H24ClN2·HCl
Molecular Weight	351.32 g/mol
Synonyms	3-Chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine Hydrochloride; Clomipramine HCl; Anafranil (trade name); Hydiphen; Maronil; Chlorimipramine Hydrochloride; G-34586; NSC-169015
EINECS	241-350-0

Quality Control

Our Clomipramine Hydrochloride is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, impurity profiles, and compliance with relevant pharmacopeial monographs. Our quality commitment ensures supply chain reliability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Solubility	Freely soluble in water and methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.