Description

Meta-(Trifluoromethyl)-Cinnamicacid is a high-purity fluorinated organic building block characterized by its cinnamic acid core and a meta-positioned trifluoromethyl group. This compound matters for its unique combination of aromaticity, acidity, and the lipophilicity and metabolic stability imparted by the fluorine atoms, making it a valuable synthon in advanced chemical synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional molecules.

Application

• Key intermediate in the synthesis of pharmaceutical candidates, particularly those targeting CNS and inflammatory diseases.
• Building block for advanced agrochemicals, such as herbicides and fungicides, leveraging the trifluoromethyl group's bioactivity.
• Precursor for liquid crystal materials and organic electronic components in the display industry.
• Starting material for metal-organic frameworks (MOFs) and specialty polymers with tailored properties.
• Use in academic and industrial research for studying structure-activity relationships (SAR) in medicinal chemistry.
• Intermediate for producing dyes, pigments, and UV absorbers in fine chemical manufacturing.

Basic Information

Product Name	Meta-(Trifluoromethyl)-Cinnamicacid
CAS No.	16642-87-8
Molecular Formula	C10H7F3O2
Molecular Weight	216.16 g/mol
Synonyms	3-(Trifluoromethyl)cinnamic acid; (E)-3-[3-(Trifluoromethyl)phenyl]prop-2-enoic acid; m-(Trifluoromethyl)cinnamic acid; 3-(Trifluoromethyl)benzeneacrylic acid; (E)-3-(3-(Trifluoromethyl)phenyl)acrylic acid; α,3-Bis(trifluoromethyl)cinnamic acid (common misnomer, verify structure); 3-CF3-Cinnamic Acid
EINECS	Contact for details

Quality Control

Our Meta-(Trifluoromethyl)-Cinnamicacid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.