Description

Butriptyline is a tricyclic antidepressant (TCA) compound with the CAS registry number 15686-37-0. It is valued in pharmaceutical research and development for its specific neurochemical activity profile, which serves as a reference point for studying antidepressant mechanisms. This compound is primarily utilized by pharmaceutical manufacturers, research institutions, and analytical laboratories engaged in the development and quality control of psychotropic medications.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the identification, purity assay, and impurity profiling of active pharmaceutical ingredients (APIs) in quality control laboratories.
• Biochemical Research: Employed in preclinical studies to investigate the pharmacology, metabolism, and structure-activity relationships (SAR) of tricyclic antidepressant agents.
• Analytical Method Development: Serves as a key analyte for developing and validating analytical methods, such as High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS), for antidepressant compounds.
• Metabolite Synthesis: Acts as a precursor or intermediate in the synthesis of specific metabolites for pharmacokinetic and toxicological studies.

Basic Information

Product Name	Butriptyline
CAS No.	15686-37-0
Molecular Formula	C21H27N
Molecular Weight	293.45 g/mol
Synonyms	10,11-Dihydro-N,N,β-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propylamine; Butriptyline Hydrochloride (salt form); Evadyne; Centroton; 5-(3-Methylaminopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene; Wy-2245; NSC-112682
EINECS	Contact for details

Quality Control

Our Butriptyline is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP (current Good Manufacturing Practice) and ICH (International Council for Harmonisation) guidelines for pharmaceutical ingredients, ensuring the material is suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.