Description

Pentafluorophenyloxy-Acetic Acid Ethyl Ester is a high-purity fluorinated organic building block essential for advanced chemical synthesis. This compound is valued for its unique reactivity profile, particularly in the formation of esters and other functional groups under demanding conditions. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors who require precise molecular architecture.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the pentafluorophenyl moiety contributes to product efficacy and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated components used in electronic display technologies and organic light-emitting diodes.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, altering surface properties, chemical resistance, and thermal stability for high-performance materials.
• Cross-coupling Reactions: Acts as a substrate in palladium-catalyzed and other metal-mediated coupling reactions to construct complex biaryl and heteroaryl structures.
• Proteomics & Bioconjugation Reagent: Utilized in the derivatization of peptides, proteins, and other biomolecules for analytical purposes or to create stable conjugates.

Basic Information

Product Name	Pentafluorophenyloxy-Acetic Acid Ethyl Ester
CAS No.	14742-37-1
Molecular Formula	C10H7F5O3
Molecular Weight	270.15 g/mol
Synonyms	Ethyl Pentafluorophenyloxyacetate; Ethyl (Pentafluorophenoxy)acetate; Acetic acid, 2-(pentafluorophenoxy)-, ethyl ester; Pentafluorophenoxyacetic Acid Ethyl Ester; 2-(Pentafluorophenoxy)acetic Acid Ethyl Ester; Ethyl 2-(Perfluorophenoxy)acetate; PFP-O-CH2-COOEt
EINECS	Contact for details

Quality Control

Every batch of Pentafluorophenyloxy-Acetic Acid Ethyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its organic ester nature, it should be handled in accordance with good laboratory practices for chemical storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.