Description

3-(10,11-Dihydro-5H-Dibenzo[A,D]Cyclohepten-5-Ylidene)Propyl(Methyl)Ammonium p-Toluenesulphonate is a high-purity organic salt compound, identified by CAS NO 14675-77-5, valued for its role as a key pharmaceutical intermediate and research chemical. Its molecular structure makes it a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in neurological and psychiatric therapeutic areas. This compound is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and advanced material sectors seeking reliable, high-quality synthetic intermediates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of tricyclic antidepressant compounds and related central nervous system (CNS) active drugs.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in multi-step synthetic routes to construct complex molecular frameworks for target-specific medications.
• Biochemical Research: Serves as a standard or reagent in neurological and pharmacological research studies.
• Agrochemical Development: Potential intermediate in the synthesis of specialty agrochemicals requiring specific ammonium salt functionalities.
• Organic Synthesis: Employed in academic and industrial laboratories for the development of novel organic compounds and material science applications.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of related pharmaceutical products.

Basic Information

Product Name	3-(10,11-Dihydro-5H-Dibenzo[A,D]Cyclohepten-5-Ylidene)Propyl(Methyl)Ammonium p-Toluenesulphonate
CAS No.	14675-77-5
Molecular Formula	C26H29NO3S
Molecular Weight	435.58 g/mol
Synonyms	N-Methyl-3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-propanaminium 4-methylbenzenesulfonate; Protriptyline p-Toluenesulfonate Salt; Protriptyline Tosylate; 5-(3-(Methylamino)propylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene p-toluenesulfonate; MK-240 p-toluenesulfonate; Protriptyline p-Toluenesulphonate; Protriptyline Tosylate Salt; 14675-77-5
EINECS	Contact for details

Quality Control

Our 3-(10,11-Dihydro-5H-Dibenzo[A,D]Cyclohepten-5-Ylidene)Propyl(Methyl)Ammonium p-Toluenesulphonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Unknown Impurity	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.