Description

2-Bromo-4-Fluorobenzoic Acid is a halogenated benzoic acid derivative serving as a versatile and critical building block in advanced organic synthesis. Its value lies in the strategic positioning of bromine and fluorine atoms on the aromatic ring, which allows for selective functionalization and the introduction of unique physicochemical properties into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring halogenated aromatic scaffolds for bioactivity.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where the fluorine atom can enhance metabolic stability and lipophilicity.
• Liquid Crystal & OLED Material Production: Serves as a building block for creating halogenated aromatic cores in advanced electronic and display materials.
• Organic Ligand Preparation: Utilized to synthesize specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic pathways and creating novel chemical entities.

Basic Information

Item	Details
Product Name	2-Bromo-4-Fluorobenzoic Acid
CAS No.	14632-85-0
Molecular Formula	C7H4BrFO2
Molecular Weight	219.01 g/mol
Synonyms	4-Fluoro-2-bromobenzoic Acid; 2-Bromo-4-fluorobenzoic Acid; Benzoic acid, 2-bromo-4-fluoro-; 2-Bromo-4-fluorobenzenecarboxylic acid; 14632-85-0; 4-Fluoro-o-bromobenzoic Acid; o-Bromo-p-fluorobenzoic Acid; 2-Br-4-F-C6H3-COOH
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluorobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.