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5H-Dibenzo[A,D]Cycloheptene-5-Propanamine CAS NO 14451-08-2


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CAS No.:14451-08-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5H-Dibenzo[A,D]Cycloheptene-5-Propanamine is a high-purity organic intermediate of significant importance in advanced pharmaceutical synthesis. This compound serves as a critical building block for the development of tricyclic antidepressant analogs and other active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors requiring precise and reliable synthetic precursors.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of tricyclic antidepressant compounds and related central nervous system (CNS) active drugs.
  • Organic Synthesis Building Block: Used in research and development for constructing complex polycyclic molecular frameworks.
  • Agrochemical Research: Serves as a starting material for developing novel active ingredients with specific biological activity.
  • Academic & Industrial R&D: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and new chemical entity (NCE) discovery.
  • Fine Chemical Production: Used in the manufacture of specialty chemicals requiring a dibenzocycloheptene core structure.

Basic Information

Item Detail
Product Name 5H-Dibenzo[A,D]Cycloheptene-5-Propanamine
CAS No. 14451-08-2
Molecular Formula C₁₈H₁₉N
Molecular Weight 249.35 g/mol
Synonyms 5-(3-Aminopropyl)-5H-dibenzo[a,d]cycloheptene; 5H-Dibenzo[a,d]cyclohepten-5-ylpropylamine; 3-(5H-Dibenzo[a,d]cyclohepten-5-yl)propan-1-amine; Nortriptyline Impurity; Nortriptyline Related Compound A; Dibenzo[a,d]cycloheptene-5-propanamine; 5-(3-Aminopropyl)dibenzo[a,d]cycloheptene
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Quality Control

Our 5H-Dibenzo[A,D]Cycloheptene-5-Propanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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