Description

3β,15β-Di(Acetyloxy)-14-Hydroxy-5α-Card-20(22)-Enolide is a high-purity, semi-synthetic cardiac glycoside derivative, a key intermediate in the synthesis of potent cardioactive pharmaceuticals. Its value lies in providing a structurally defined and reliable starting point for advanced pharmaceutical research and development, ensuring consistent results in critical synthetic pathways. This compound is essential for R&D chemists and manufacturers in the pharmaceutical industry, particularly those focused on developing novel cardiovascular therapeutics and studying structure-activity relationships of digitalis-like compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of advanced cardioactive drugs and their analogs.
• Research & Development: Used in medicinal chemistry for studying the pharmacological activity and metabolic pathways of cardiac glycosides.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating the interaction of cardiac glycosides with sodium-potassium ATPase (Na+/K+-ATPase) pumps.
• Process Chemistry: Utilized for scaling up and optimizing synthetic routes to complex steroidal molecules in pilot plants.

Basic Information

Item	Details
Product Name	3β,15β-Di(Acetyloxy)-14-Hydroxy-5α-Card-20(22)-Enolide
CAS No.	14155-62-5
Molecular Formula	C29H40O8
Molecular Weight	516.63 g/mol
Synonyms	3β,15β-Diacetoxy-14-hydroxy-5α-card-20(22)-enolide; 14-Hydroxy-3β,15β-diacetoxy-5α-card-20(22)-enolide; 3β,15β-Di-O-acetyl-14-hydroxy-5α-card-20(22)-enolide; Acetylgitoxin intermediate; Gitoxin derivative; 5α-Card-20(22)-enolide, 3β,15β-bis(acetyloxy)-14-hydroxy-; 14155-62-5
EINECS	Contact for details

Quality Control

Our 3β,15β-Di(Acetyloxy)-14-Hydroxy-5α-Card-20(22)-Enolide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.