Description

Benzo[B]Thiophene-2-Carboxylic Acid, 5-Fluoro-, Ethyl Ester is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters as a critical intermediate for developing novel pharmaceuticals and agrochemicals, where its unique structure enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides where the fluorine atom enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent for creating specialty polymers and organic electronic materials.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fluorine Chemistry: Employed in methodological studies exploring new fluorination reactions and the synthesis of complex fluorinated heterocycles.

Basic Information

Item	Details
Product Name	Benzo[B]Thiophene-2-Carboxylic Acid, 5-Fluoro-, Ethyl Ester
CAS No.	13771-69-2
Molecular Formula	C11H9FO2S
Molecular Weight	224.25 g/mol
Synonyms	5-Fluorobenzo[b]thiophene-2-carboxylic acid ethyl ester; Ethyl 5-fluorobenzo[b]thiophene-2-carboxylate; 5-Fluoro-1-benzothiophene-2-carboxylic acid ethyl ester; 5-F-BT-2-COOEt; 5-Fluorobenzo[b]thien-2-carboxylic acid, ethyl ester; 13771-69-2; Ethyl 5-fluorobenzo[b]thien-2-carboxylate
EINECS	Contact for details

Quality Control

Our Benzo[B]Thiophene-2-Carboxylic Acid, 5-Fluoro-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure. Store away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.