Description

Tranylcypromine Hemisulfate CAS NO 13492-01-8 is a high-purity pharmaceutical active ingredient, specifically the hemisulfate salt of the irreversible monoamine oxidase inhibitor (MAOI) tranylcypromine. This compound is critical for research and development in neuropharmacology and serves as the key active pharmaceutical ingredient (API) in the formulation of antidepressant medications. It is primarily required by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in CNS drug discovery and production.

Application

• Pharmaceutical API: Primary active ingredient in the manufacture of antidepressant drugs.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control and method validation.
• Biochemical Research: Essential tool for studying monoamine oxidase (MAO) enzyme inhibition mechanisms and neurotransmitter regulation.
• Preclinical Development: Utilized in pharmacological studies and animal models for depression and related CNS disorders.
• Formulation Development: Serves as a model compound for developing novel drug delivery systems for CNS-targeted therapies.

Basic Information

Product Name	Tranylcypromine Hemisulfate
CAS No.	13492-01-8
Molecular Formula	C9H11N • ½H2SO4
Molecular Weight	196.25 g/mol (free base: 133.19)
Synonyms	trans-2-Phenylcyclopropylamine hemisulfate; (±)-Tranylcypromine hemisulfate; Parnate (salt); SKF Trans-385; NSC 114649; trans-2-Phenylcyclopropanamine hemisulfate; DL-Tranylcypromine hemisulfate
EINECS	Contact for details

Quality Control

Our Tranylcypromine Hemisulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.