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2,4,5-Trifluoro-3-Methoxybenzoic Acid CAS NO 11281-65-5


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CAS No.:11281-65-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,4,5-Trifluoro-3-Methoxybenzoic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique substitution pattern, which introduces both fluorine atoms and a methoxy group to precisely modulate the electronic and steric properties of target molecules. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates in oncology and central nervous system (CNS) therapeutic areas.
  • Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
  • Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays (LCDs).
  • Organic Electronic Materials: Employed in the development of organic semiconductors and electron-transport materials for OLEDs and photovoltaic cells.
  • Chemical Research & Development: A versatile reagent for introducing a trifluoromethoxybenzoyl moiety in medicinal chemistry and material science research.
  • Complex Ligand Synthesis: Used to create specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name 2,4,5-Trifluoro-3-Methoxybenzoic Acid
CAS No. 11281-65-5
Molecular Formula C8H5F3O3
Molecular Weight 206.12 g/mol
Synonyms 3-Methoxy-2,4,5-trifluorobenzoic Acid; 2,4,5-Trifluoro-3-methoxybenzoic Acid; Benzoic acid, 2,4,5-trifluoro-3-methoxy-; 2,4,5-Trifluoro-m-anisic Acid
EINECS Contact for details

Quality Control

Our 2,4,5-Trifluoro-3-Methoxybenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥98.0%
Melting Point Contact for details
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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