Description

Tosyllysine α-Naphthyl Ester is a specialized biochemical reagent primarily used as a chromogenic substrate for enzyme activity assays. This compound is valued for its role in detecting and quantifying the activity of specific proteolytic enzymes, particularly trypsin and related serine proteases. It is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic reagent manufacturing sectors who require precise enzymatic analysis.

Application

• Enzymatic Substrate for Trypsin: Serves as a key chromogenic substrate in biochemical assays to measure trypsin activity through colorimetric detection.
• Protease Research & Development: Used in R&D laboratories for studying the kinetics, inhibition, and specificity of serine proteases.
• Diagnostic Reagent Manufacturing: A critical raw material in the production of diagnostic kits and reagents for clinical and research use.
• Pharmaceutical Quality Control: Employed in QC processes to test the enzymatic activity of biopharmaceutical products, including pancreatic enzyme supplements.
• Biochemical Teaching & Education: Utilized in academic settings for practical demonstrations of enzyme-substrate interactions and assay methodologies.
• Food Science Analysis: Applied in food industry laboratories to assess protease activity in products or during processing.

Basic Information

Product Name	Tosyllysine α-Naphthyl Ester
CAS No.	10318-07-7
Molecular Formula	C24H28N2O5S
Molecular Weight	456.56 g/mol
Synonyms	Nα-Tosyl-L-lysine α-naphthyl ester; TLNE; TAME (Note: TAME is also a common name for p-Toluenesulfonyl-L-arginine methyl ester, use with caution); Tosyl-L-lysine 1-naphthyl ester; L-Lysine, N6-(1-naphthalenyloxy)-, N2-[(4-methylphenyl)sulfonyl]-; Trypsin chromogenic substrate; Chromogenic trypsin substrate; 10318-07-7
EINECS	Contact for details

Quality Control

Our Tosyllysine α-Naphthyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in alcohols
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.